Reviews: Clinical Applications of Blood-Derived and Marrow-Derived Stem Cells for Nonmalignant Diseases by Richard K. Burt

by Alexey Bersenev on April 8, 2008 · 2 comments

in reviews

This review is remarkable! It is a product of the work of clinicians who were brave enough and pioneered hematopoietic stem cell transplantation for treatment of non-malignant diseases in the clinic. 20 years of history. Success and pitfalls.

The best team, led by Richard Burt at Northwestern University Feinberg School of Medicine (Chicago, IL) tells us about the history of the first trials, observing current trials and gives a prognosis for future perspectives.

Must read!

EVIDENCE ACQUISITION: Search of multiple electronic databases (MEDLINE, EMBASE, Science Citation Index), US Food and Drug Administration [FDA] Drug Site, and National Institutes of Health Web site to identify studies published from January 1997 to December 2007 on use of hematopoietic stem cells (HSCs) in autoimmune, cardiac, or vascular diseases. The search was augmented by hand searching of reference lists in clinical trials, review articles, proceedings booklets, FDA reports, and contact with study authors and device and pharmaceutical companies.

I was impressed by how the authors designed this review:

full text (pdf)


{ 2 comments… read them below or add one }

cc April 9, 2008 at 8:53 pm

This is wonderful! I wonder if the general population realizes the benefits of stem cells because I always read about people opposing it. I wonder if they know the difference between using embryonic SCs and adult SCs… Thanks for sharing the video!


Alex April 9, 2008 at 9:15 pm

“people opposing it” because people watch TV too much,
embryonic stem cells on the mass media and in scandals, because of “destroying human life”… not adult stem cells which are in the clinic 50 years at least, since first bone marrow transplant procedure
People don’t know difference that’s why opposing it,
we’re going to educate them more


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